BDBM50580515 CHEMBL5088622

SMILES Nc1nc-2c(Cc3ccc(OCCCN4CCCC4)cc-23)c(n1)-c1ccccc1

InChI Key InChIKey=BDUVGZUKNGPFEZ-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50580515   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi:  11nMAssay Description:Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D3 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]SCH23390 from human recombinant dopamine D5 receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2S receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in sf9 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50580515(CHEMBL5088622)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine as substrate measured for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed