BDBM50581762 GB-0139::GB0139::OLITIGALTIN::Olitigaltin::TD-139::TD139::Td 139::Td-139::Td139

SMILES OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1

InChI Key InChIKey=YGIDGBAHDZEYMT-MQFIMZJJSA-N

Data  4 IC50

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50581762   

TargetGalectin-3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGalectin-3(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human Gal3-induced chemotaxis using human monocyte incubated for 4 hrs by calcein-AM dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGalectin-3(Mus musculus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of moues Gal3-induced hemagglutination using mouse RBC incubated for overnight by hemagglutination assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGalectin-3(Mus musculus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of biotin-asialofetuin binding to mouse Gal3 measured after 90 mins by HTRF competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB