BDBM50582879 CHEMBL5088515

SMILES CN([C@H]1CCN(C1)[C@H]1CCC[C@H](C1)NC(=O)c1cc2c(F)ccc(C)c2[nH]1)C(C)=O

InChI Key InChIKey=XHVWORJNXNUHPG-SQNIBIBYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582879   

TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50582879(CHEMBL5088515)
Affinity DataIC50:  127nMAssay Description:Inhibition of SETD2 in human A549 cells assessed as H3K36 trimethyl mark incubated for 3 days by in-cell western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50582879(CHEMBL5088515)
Affinity DataIC50:  23nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed