BDBM50582950 CHEMBL5075535

SMILES OC(=O)c1cn(C2CC2)c2cc(N3CCN(CCC(=O)Nc4ccc(cc4)S(=O)(=O)Nc4cncc(Cl)n4)CC3)c(F)cc2c1=O

InChI Key InChIKey=NCIFTFPQZBACJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582950   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50582950(CHEMBL5075535)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity using pBR322 as substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50582950(CHEMBL5075535)
Affinity DataIC50:  440nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed