BDBM50585086 CHEMBL5088157

SMILES COc1cccc(c1)-c1nc2sccn2c1-c1ccnc(NCCN2CCN(Cc3ccccc3)S2(=O)=O)n1

InChI Key InChIKey=IVIOUFGAVRASMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585086   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585086(CHEMBL5088157)
Affinity DataIC50:  17nMAssay Description:Inhibition of human wild type BRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585086(CHEMBL5088157)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human wild type CRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585086(CHEMBL5088157)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed