BDBM50585094 CHEMBL5088891

SMILES CC1(C)CN(CCNc2nccc(n2)-c2c(nc3sccn23)-c2cccc(O)c2)S(=O)(=O)N1

InChI Key InChIKey=VYMHXRQVMRBRMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585094   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585094(CHEMBL5088891)
Affinity DataIC50:  10nMAssay Description:Inhibition of human wild type BRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585094(CHEMBL5088891)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human wild type CRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585094(CHEMBL5088891)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed