BDBM50585281 CHEMBL5079623
SMILES C[C@H](C(O)=O)n1nc(Cn2cc3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O
InChI Key InChIKey=PMFUQAVMFHEJFO-CYBMUJFWSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50585281
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as inhibition of calcium fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human S1P2 in HFL1 cells assessed as inhibition of EC80 S1P-induced IL8 release incubated for 16 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity against human S1P2 assessed as inhibition of beta-arrestin 2 recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP450 in human liver microsomesMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 3.58E+4nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Antagonist activity at human S1P2 in HFL1 cells assessed as inhibition of EC80 S1P-induced IL8 release incubated for 16 to 24 hrs in presence of 2% H...More data for this Ligand-Target Pair