BDBM50586346 CHEMBL5079099
SMILES C[C@H]1CN(CCN1c1nc(OCc2cn(C)cn2)nc2C[C@H](CCc12)c1cc(O)cc2ccccc12)C(=O)C=C
InChI Key InChIKey=WRRIEBSQCWUQBF-UNMCSNQZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50586346
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of KRAS G12C mutant in human HCC1171 cells assessed as effect on cell alkylation measured after 18 hrs by western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of KRAS G12C mutant (2 to 188 residues) (unknown origin) expressed in Escherichia coli assessed as inhibition of SOS mediated nucleotide e...More data for this Ligand-Target Pair