BDBM50587478 CHEMBL5091585

SMILES CCOc1ccc2c(c1)c1ccsc1[nH]c2=O

InChI Key InChIKey=LKASVOXYBOMEHH-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50587478   

TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50587478(CHEMBL5091585)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PARP15 (482 to 678 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 3 hrs by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50587478(CHEMBL5091585)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP14 (unknown origin) using NAD+ as substrate incubated for 18 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50587478(CHEMBL5091585)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PARP2 (1 to 583 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50587478(CHEMBL5091585)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of TNKS2 (873 to 1161 residues) (unknown origin) expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50587478(CHEMBL5091585)
Affinity DataIC50:  920nMAssay Description:Inhibition of PARP10 (809 to 1017 residues) (unknown origin) expressed in Escherichia coli using NAD+ as substrate incubated for 13 hrs by fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed