BDBM50587619 CHEMBL5205436

SMILES COc1cc(OC)c(Cl)c(CCc2cc(n[nH]2)-c2nc3ccc(cc3[nH]2)N2CCN(C)CC2)c1Cl

InChI Key InChIKey=CGXQXIOHFLFFRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50587619   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587619(CHEMBL5205436)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human FGFR2 (399 to 821 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587619(CHEMBL5205436)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human FGFR1 (398 to 822 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587619(CHEMBL5205436)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human KDR (790 to 1356 residues) expressed in baculovirus expression system using IGF-1Rtide peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587619(CHEMBL5205436)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR3 (436 to 806 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed