BDBM50587621 CHEMBL5179660

SMILES COc1cc(CCc2cc(n[nH]2)-c2nc3cc(F)c(cc3[nH]2)N2C[C@H](C)O[C@H](C)C2)cc(OC)c1

InChI Key InChIKey=QUDUPSBANJZEIW-IYBDPMFKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50587621   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587621(CHEMBL5179660)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human FGFR2 (399 to 821 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587621(CHEMBL5179660)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human FGFR1 (398 to 822 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587621(CHEMBL5179660)
Affinity DataIC50:  301nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human KDR (790 to 1356 residues) expressed in baculovirus expression system using IGF-1Rtide peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587621(CHEMBL5179660)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR3 (436 to 806 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed