BDBM50587677 CHEMBL5173501
SMILES C[C@H]1CNC(=O)c2cnn3cc(N[C@H](C)c4cc(F)cc(O1)c4)cnc23
InChI Key InChIKey=SBLCPBDVMUSESZ-WDEREUQCSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50587677
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair