BDBM50587679 CHEMBL5199998

SMILES CC1(C)C(=O)N([C@H]2CCc3c2cccc3O)c2nc(ncc12)S(C)(=O)=O

InChI Key InChIKey=LZUYOYKXEXENTQ-ZDUSSCGKSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50587679   

TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587679(CHEMBL5199998)
Affinity DataIC50:  3nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase SIK1(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587679(CHEMBL5199998)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST fused recombinant SIK1 in HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser162 incubated for 1 hr in presence of ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 2(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587679(CHEMBL5199998)
Affinity DataIC50:  120nMAssay Description:Inhibition of NUAK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase SIK3(Homo sapiens)
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587679(CHEMBL5199998)
Affinity DataIC50:  43nMAssay Description:Inhibition of GST fused recombinant SIK3 in HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser370 incubated for 1 hr in presence of ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase SIK2(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587679(CHEMBL5199998)
Affinity DataIC50:  12nMAssay Description:Inhibition of GST fused recombinant SIK2 in HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser329 incubated for 1 hr in presence of ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed