BDBM50587679 CHEMBL5199998
SMILES CC1(C)C(=O)N([C@H]2CCc3c2cccc3O)c2nc(ncc12)S(C)(=O)=O
InChI Key InChIKey=LZUYOYKXEXENTQ-ZDUSSCGKSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50587679
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase SIK1(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of GST fused recombinant SIK1 in HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser162 incubated for 1 hr in presence of ATP ...More data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 2(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of NUAK2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase SIK3(Homo sapiens)
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of GST fused recombinant SIK3 in HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser370 incubated for 1 hr in presence of ATP ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase SIK2(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of GST fused recombinant SIK2 in HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser329 incubated for 1 hr in presence of ATP ...More data for this Ligand-Target Pair