BDBM50588316 CHEMBL5170657

SMILES CCc1cccc(CC)c1-n1c(O)c(C(=O)N2CC[C@H](C2)c2ncc(Cl)cc2F)c(=O)nc1-c1ccn(C)n1

InChI Key InChIKey=BFXUALMCVABIFZ-GOSISDBHSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588316   

TargetApelin receptor(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50588316(CHEMBL5170657)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I] Apelin-13 from human APJ expressed in HEK293FT cells incubated for 2 hrs by microbeta scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetApelin receptor(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50588316(CHEMBL5170657)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at human APJ expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production incubated for 60 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails PubMed