BDBM50588453 CHEMBL5201013

SMILES COc1cccc(O[C@@H]2CCC[C@H]2Nc2ncnc3n(cnc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1

InChI Key InChIKey=BXIXAVMJHWVWHC-NKYRPOHVSA-N

Data  2 KI  2 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50588453   

TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588453(CHEMBL5201013)
Affinity DataKi:  245nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused human adenosine A1 receptor expressed in HEK293 cells measured for 10 mins by NanoBRET competition bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588453(CHEMBL5201013)
Affinity DataKi:  275nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused rat adenosine A1 receptor expressed in HEK293 cells measured for 10 mins by NanoBRET competition bind...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588453(CHEMBL5201013)
Affinity DataKd:  126nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused human adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588453(CHEMBL5201013)
Affinity DataKd:  263nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused rat adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588453(CHEMBL5201013)
Affinity DataEC50:  0.525nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588453(CHEMBL5201013)
Affinity DataEC50:  5.75E+3nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed