BDBM50588462 CHEMBL5195714

SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCC[C@H]3Oc3ccccc3Cl)ncnc12

InChI Key InChIKey=GGSMZHDDHVZCIH-IADDZVCRSA-N

Data  2 KI  2 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50588462   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataKi:  25nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused rat adenosine A1 receptor expressed in HEK293 cells measured for 10 mins by NanoBRET competition bind...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataKi:  41nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused human adenosine A1 receptor expressed in HEK293 cells measured for 10 mins by NanoBRET competition bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataKd:  13nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused rat adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human adenosine A3 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataKd:  22nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused human adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataEC50:  2.14E+3nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataEC50:  0.123nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50588462(CHEMBL5195714)
Affinity DataEC50:  603nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed