BDBM50588744 CHEMBL5189383

SMILES COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2nc(cnc2c1)-c1cnn(C)c1

InChI Key InChIKey=YYMGAHUGGLEVAR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50588744   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50588744(CHEMBL5189383)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50588744(CHEMBL5189383)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human FGFR1 using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50588744(CHEMBL5189383)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human FGFR4 (460 to 802 residues) using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50588744(CHEMBL5189383)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of N-terminal GST tagged recombinant human FGFR2 (400 to 821 residues) expressed in an Sf9 infected baculovirus expression system using bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Prelude Therapeutics

Curated by ChEMBL
LigandPNGBDBM50588744(CHEMBL5189383)
Affinity DataIC50:  68nMAssay Description:Inhibition of recombinant human FGFR3 V555M mutant using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed