BDBM50589732 CHEMBL5207619::US11760752, Compound 39

SMILES Cc1cc(Oc2ccc(Cn3nc4ccc(Cl)cc4c3C(=O)NS(=O)(=O)c3ccc(NCc4ccncc4)c(c3)[N+]([O-])=O)cc2)cc(C)c1Cl

InChI Key InChIKey=LHJJUWPFTJRQBD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50589732   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM50589732(CHEMBL5207619 | US11760752, Compound 39)
Affinity DataKi:  1.52E+3nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM50589732(CHEMBL5207619 | US11760752, Compound 39)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition of BCL-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50589732(CHEMBL5207619 | US11760752, Compound 39)
Affinity DataKi:  1.65E+3nMAssay Description:Inhibition of MCL-1 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50589732(CHEMBL5207619 | US11760752, Compound 39)
Affinity DataKi:  1.65E+3nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM50589732(CHEMBL5207619 | US11760752, Compound 39)
Affinity DataKi: >1.00E+4nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50589732(CHEMBL5207619 | US11760752, Compound 39)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of BCL-xL (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed