BDBM50591075 CHEMBL5200118

SMILES CNC(=O)[C@]1(C)CC[C@H](C1)Nc1ncc2c(Br)nn(-c3ccc(-c4nnc(C)s4)c(CCS(C)(=O)=O)c3)c2n1

InChI Key InChIKey=LSWRRAICGUIZHV-PUAOIOHZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591075   

TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591075(CHEMBL5200118)
Affinity DataIC50:  9nMAssay Description:Inhibition of GCN2 in human SK-OV-3 cells assessed as reduction in phosphorylation of eIF2alpha by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591075(CHEMBL5200118)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed