BDBM50592008 CHEMBL5171168::US20240018135, Code A-34

SMILES CC1CN(CC(=O)Nc2ccc(Cl)cc2)CCN1Cc1cnc(NC(C)=O)s1

InChI Key InChIKey=IILJNGRUWDDWLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50592008   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50592008(CHEMBL5171168 | US20240018135, Code A-34)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant OGA pretreated for 20 mins followed by 4-Methylumbelliferyl N-acetyl-(3-D-glucosaminide substrate addition by fluorom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50592008(CHEMBL5171168 | US20240018135, Code A-34)
Affinity DataIC50:  50nMAssay Description:Human OGA (recombinant hOGA protein, advanced Protein Technologies corp., Korea) enzyme reaction was performed in a reaction solution containing 25 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50592008(CHEMBL5171168 | US20240018135, Code A-34)
Affinity DataIC50:  50nMAssay Description:Human OGA (recombinant hOGA protein, advanced Protein Technologies corp., Korea) enzyme reaction was performed in a reaction solution containing 25 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent