BDBM50592071 CHEMBL5169684

SMILES OC(=O)c1ccnc(c1)C(=O)NS(=O)(=O)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=OCYAGXIPGJZUJN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50592071   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged FTO (1 to 505 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRNA demethylase ALKBH5(Homo sapiens)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human full length N-terminal His6-tagged ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA oxidative demethylase ALKBH2(Homo sapiens)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRNA demethylase ALKBH5(Homo sapiens)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of N-terminal truncated human ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of full length human FTO (1 to 505 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA oxidative demethylase ALKBH2(Homo sapiens)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human ALKBH3 expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH3 (1 to 286 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed