BDBM50592246 T3-CLK

SMILES CN1CCN(CC1)C(=O)C(C)(C)c1ccc(cc1)C(=O)Nc1cn2cc(ccc2n1)-c1ccncc1

InChI Key InChIKey=IEFFSHLHNYVSEF-UHFFFAOYSA-N

Data  6 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50592246   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of N-terminal FLAG-tagged human Clk1 using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition measured af...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50:  15nMAssay Description:Inhibition of N-terminal FLAG-tagged human Clk2 using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition measured af...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CLK2 by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50:  110nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592246(T3-CLK)
Affinity DataIC50:  260nMAssay Description:Inhibition of N-terminal FLAG-tagged human DYRK1A using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition measured ...More data for this Ligand-Target Pair
In DepthDetails PubMed