BDBM50592357 CHEMBL5185685

SMILES CCOC(=O)Nc1cc(F)c(NCc2ccc(cc2)C(F)(F)F)c(F)c1N

InChI Key InChIKey=DLTUKHNOWLHZDN-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50592357   

TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592357(CHEMBL5185685)
Affinity DataEC50:  50nMAssay Description:Agonist activity at Kv7.2 (unknown origin) assessed as shifting of voltage dependent activation to more negative potentials by SyncroPatch assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592357(CHEMBL5185685)
Affinity DataEC50:  1.06E+3nMAssay Description:Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592357(CHEMBL5185685)
Affinity DataEC50:  87nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592357(CHEMBL5185685)
Affinity DataEC50:  790nMAssay Description:Agonist activity at Kv7.2/3 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed