BDBM50592735 CHEMBL5201983

SMILES [2H]c1c([2H])c([2H])c([C@@H]2C[C@@H](N3CCNC(C)(C)C3)c3cc(Cl)ccc23)c([2H])c1[2H]

InChI Key InChIKey=FBCSWIXKXHSYBN-LSQWYULJSA-N

Data  20 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50592735   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  0.390nMAssay Description:Displacement of [125I](+/-)DOI from recombinant human 5-HT2B receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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TargetD(1B) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]SCH 23390 from recombinant human D5 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT6 receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  0.840nMAssay Description:Displacement of [125I](+/-)DOI from recombinant human 5-HT2A receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  1nMAssay Description:Displacement of [3H]SCH 23390 from recombinant human D1 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  1.10nMAssay Description:Displacement of [125I](+/-)DOI from recombinant human 5-HT2C receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetHistamine H1 receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]pyrilamine from recombinant human H1 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  11nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  11nMAssay Description:Displacement of [3H]7-OH-DPAT from recombinant human D2S receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  11nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha1B receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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TargetD(4) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  11nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D4.4 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  13nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha1A receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  35nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha1D receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetD(3) dopamine receptor(Homo sapiens)
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  59nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  160nMAssay Description:Displacement of [3H]RX 821002 from recombinant human alpha2C receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  420nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  490nMAssay Description:Displacement of [3H]RX 821002 from recombinant human alpha2B receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  510nMAssay Description:Displacement of [3H]BTCP from recombinant human DAT measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  660nMAssay Description:Displacement of [125I]CYP from rat brain 5HT1B receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50592735(CHEMBL5201983)Copy SMILESCopy InChI

Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]RX 821002 from recombinant human alpha2A receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI