BDBM50592781 CHEMBL5203413
SMILES CC#CCOc1ccc2cc(oc2c1)C(c1ccc(cc1)C#N)n1cncn1
InChI Key InChIKey=VCZRCOBTYSEEQW-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50592781
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using ethoxyresorufin as substrate and measured by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate and measured by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate and measured by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using Dextromethorphan as substrate and measured by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate and measured by LC-MS/MS analysisMore data for this Ligand-Target Pair