BDBM50593700 CHEMBL5193024
SMILES CN1CC2(CC(C2)n2cc(Nc3nc(NC4(C)CC4)c4c(ccn(C)c4=O)n3)cn2)C1
InChI Key InChIKey=HRFWKBWFXMXLPG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50593700
Affinity DataIC50: 33nMAssay Description:Inhibition of IRAK4 in IL1-stimulated human KARPAS-299 cells assessed as fluorescence intensityMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant IRAK4 assessed as unphosphorylated KKARFSRFAGSSPSQSSMVAR peptide substrate measured after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair