BDBM50593996 CHEMBL5198615

SMILES COc1cc(OCc2cccc(Br)c2)ccc1C(N)=O

InChI Key InChIKey=XLCVIUNLASFRSY-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50593996   

TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50593996(CHEMBL5198615)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PARP-10 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50593996(CHEMBL5198615)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50593996(CHEMBL5198615)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human N-terminal 6His-tagged TNKS2 (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50593996(CHEMBL5198615)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PARP14 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50593996(CHEMBL5198615)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PARP2 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50593996(CHEMBL5198615)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB