BDBM50594012 CHEMBL5191676

SMILES CC#Cc1ccc2c(nc(CSc3ncccn3)[nH]c2=O)c1C

InChI Key InChIKey=VRECINGNBPANGK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50594012   

TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50:  14nMAssay Description:Inhibition of human full length GFP-tagged PARP11 in human HeLa cells incubated for 3 hrs by chemiluminescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50:  9.28E+3nMAssay Description:Inhibition of PARP10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50:  14nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PARP15 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed