BDBM50594746 CHEMBL5193128

SMILES NC(=O)C1C2NCC[C@@H](C3CCN(CC3)C(=O)C=C)N2N=C1c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=PZWSKESWDIFAFK-MUKMJDFVSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50594746   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  44nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  50nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  21nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  88nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594746(CHEMBL5193128)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed