BDBM50596052 CHEMBL5196484

SMILES Cc1c(Nc2ccncc2C(=O)NNC(=O)\C=C\C(O)=O)cc(Cl)c(Nc2ccccc2[N+]([O-])=O)c1Cl

InChI Key InChIKey=LIJIAAXHNOJKMP-VOTSOKGWSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596052   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataIC50:  87nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRNA demethylase ALKBH5(Homo sapiens)
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataIC50:  8.98E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin) demethylation activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataKd:  28nMAssay Description:Binding affinity to FTO (unknown origin) assessed as dissociation constant at 180 uM by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails PubMed