BDBM50596221 CHEMBL5186575

SMILES Nc1ncc(-c2cnn(c2)C2CCNCC2)c2CCN(C3CCCCC3)C(=O)c12

InChI Key InChIKey=DUGKWSLUPDXHDO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50596221   

TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50596221(CHEMBL5186575)
Affinity DataIC50:  15nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50596221(CHEMBL5186575)
Affinity DataIC50:  181nMAssay Description:Inhibition of ALK2 in human HeLa cells assessed as inhibition of SMAD1 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50596221(CHEMBL5186575)
Affinity DataIC50:  171nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50596221(CHEMBL5186575)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed