BDBM50597192 CHEMBL5175347

SMILES Cn1nc(-c2ccccc2)c2cnnc(N3CCOCC3)c12

InChI Key InChIKey=ZMGCMNQAPWXRRM-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50597192   

TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50597192(CHEMBL5175347)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of CA200645 from NLuc human A1 receptor expressed in HEK293 cells assessed as inhibition constant by NanoBRET binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50597192(CHEMBL5175347)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of CA200645 from NLuc human A3 receptor expressed in HEK293 cells assessed as inhibition constant by NanoBRET binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50597192(CHEMBL5175347)
Affinity DataEC50:  0.977nMAssay Description:Antagonist activity at human wild type A1R expressed in CHO-K1 cells assessed as inhibition of forskolin/ NECA-stimulated cAMP accumulation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50597192(CHEMBL5175347)
Affinity DataEC50:  0.316nMAssay Description:Antagonist activity at human wild type A3R expressed in Flp-In-CHO cells assessed as inhibition of forskolin/ NECA-stimulated cAMP accumulation by me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed