BDBM50597425 CHEMBL5194202

SMILES NCCSc1nc(NCc2ccc(cc2)-n2cccn2)c2[nH]nc(C3CCC3)c2n1

InChI Key InChIKey=MJACTWDJXKRKAV-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50597425   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50597425(CHEMBL5194202)
Affinity DataIC50:  4nMAssay Description:Inhibition of His-tagged CDK2/cyclin E1 (unknown origin) expressed in Sf9 cells using histone H1 as substrate in presence of ATP and [gamma33-P]ATP b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-D1(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50597425(CHEMBL5194202)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of GST-tagged CDK2/cyclin D1 (unknown origin) expressed in Sf9 cells using RPPTLSPIPHIPR peptide as substrate in presence of ATP and [gamm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase 13/Cyclin-K(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50597425(CHEMBL5194202)
Affinity DataIC50:  22nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Palack£

Curated by ChEMBL
LigandPNGBDBM50597425(CHEMBL5194202)
Affinity DataIC50:  64nMAssay Description:Inhibition of GST-tagged human CDK12/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50597425(CHEMBL5194202)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-tagged human CDK9/Cyclin T1 expressed in Sf9 cells using (YSPTSPS)2KK peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed