BDBM50597428 CHEMBL5194833
SMILES NCCSc1nc(NCc2ccc(cc2)-c2ccccn2)c2[nH]nc(C3CCCC3)c2n1
InChI Key InChIKey=JXVLTDGQDFESCZ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50597428
Affinity DataIC50: 12nMAssay Description:Inhibition of His-tagged CDK2/cyclin E1 (unknown origin) expressed in Sf9 cells using histone H1 as substrate in presence of ATP and [gamma33-P]ATP b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of GST-tagged CDK2/cyclin D1 (unknown origin) expressed in Sf9 cells using RPPTLSPIPHIPR peptide as substrate in presence of ATP and [gamm...More data for this Ligand-Target Pair
Affinity DataIC50: 334nMAssay Description:Inhibition of GST-tagged human CDK13/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
Affinity DataIC50: 304nMAssay Description:Inhibition of GST-tagged human CDK12/Cyclin K expressed in Sf9 cells using RBER-IRStide peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of GST-tagged human CDK9/Cyclin T1 expressed in Sf9 cells using (YSPTSPS)2KK peptide as substrate in presence of ATP and [gamma33-P] ATP b...More data for this Ligand-Target Pair