BDBM50597860 CHEMBL5172325

SMILES N[C@@H](CCSC[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n1cnc2c(N)ncnc12)C(O)=O

InChI Key InChIKey=ZJUKTBDSGOFHSH-XQUTYLFXSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50597860   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597860(CHEMBL5172325)
Affinity DataKi:  160nMAssay Description:Binding affinity to DOT1L (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597860(CHEMBL5172325)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597860(CHEMBL5172325)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597860(CHEMBL5172325)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed