BDBM50597867 CHEMBL5176983
SMILES CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n1ccc2c(N)ncnc12
InChI Key InChIKey=WXRGFPHDRFQODR-HZLPDVBGSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50597867
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant DOT1L (unknown origin) using 3H-SAM/chicken erythrocyte nucleosomes as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of DOT1L (unknown origin)-mediated H3K79 methylationMore data for this Ligand-Target Pair