BDBM50597867 CHEMBL5176983

SMILES CC(C)N(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n1ccc2c(N)ncnc12

InChI Key InChIKey=WXRGFPHDRFQODR-HZLPDVBGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597867   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597867(CHEMBL5176983)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant DOT1L (unknown origin) using 3H-SAM/chicken erythrocyte nucleosomes as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50597867(CHEMBL5176983)
Affinity DataIC50:  84nMAssay Description:Inhibition of DOT1L (unknown origin)-mediated H3K79 methylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed