BDBM50598322 CHEMBL5200114

SMILES FC(F)(F)c1ccc(Br)c(NC(=S)NC(=O)c2ccc3OCOc3c2)c1Br

InChI Key InChIKey=DBTFQHXBNQOCMQ-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50598322   

TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataIC50:  55nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataIC50:  3.56E+3nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataEC50:  1.08E+4nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.2 uM incubated for 30 mins by Fura-2 AM st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataEC50:  1.01E+4nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.1 uM incubated for 30 mins by Fura-2 AM st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataEC50:  1.08E+4nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.05 uM incubated for 30 mins by Fura-2 AM s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed