BDBM50598717 CHEMBL5193702::US20230348487, Example LS 6-45
SMILES [H][C@]12OC[C@@H](Oc3nc(Nc4ccc(N(C)CCN(C)C)c(NC(=O)C=C)c4)ncc3Cl)[C@@]1([H])OC[C@H]2OC
InChI Key InChIKey=MXXJXRACSRJBKS-OHUMZHCVSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50598717
Affinity DataIC50: 1.20nMAssay Description:Inhibition of GST tagged recombinant human JAK3 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human ARK5More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of human CDK16/cyclin-Y protein-protein complexMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
Affinity DataIC50: 4.73E+3nMAssay Description:Inhibition of human JAK1More data for this Ligand-Target Pair
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human JAK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.53nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 365nMAssay Description:Inhibition of human TYK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair