BDBM50598765 CHEMBL5207189

SMILES Cc1c(Cl)cccc1Nc1ccc(F)cc1C(=O)NCc1ccc(O)c(O)c1

InChI Key InChIKey=MADVKIJUDVHXOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598765   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50598765(CHEMBL5207189)
Affinity DataIC50:  4.42E+3nMAssay Description:Inhibition of human topoisomerase I assessed as DNA relaxation using DNA pBR322 as substrate incubated for 30 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
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TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50598765(CHEMBL5207189)
Affinity DataIC50:  240nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed