BDBM50599564 CHEMBL5201140

SMILES COc1cc2nc(NCCCCCC(=O)NO)nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC

InChI Key InChIKey=FDSPSLJTTWLHQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599564   

TargetHistone deacetylase 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50599564(CHEMBL5201140)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus infection system using Ac-peptide-AMC as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50599564(CHEMBL5201140)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50599564(CHEMBL5201140)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed