BDBM50599832 CHEMBL5201831

SMILES Fc1ccc(Oc2ncnc3CN(CCc23)C2=C(Cl)C(=O)NC2=O)c(c1)C(F)(F)F

InChI Key InChIKey=OCZQLQZPYCOVIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599832   

TargetShort transient receptor potential channel 5(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599832(CHEMBL5201831)
Affinity DataIC50:  60nMAssay Description:Inhibition of TRPC5 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intra...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599832(CHEMBL5201831)
Affinity DataIC50:  14nMAssay Description:Inhibition of human TRPC5 channel expressed in HEK293 cells assessed as inhibition of EA-evoked channel current measured at +80 mV by whole-cell volt...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetShort transient receptor potential channel 4(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599832(CHEMBL5201831)
Affinity DataIC50:  65nMAssay Description:Inhibition of TRPC4 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intra...More data for this Ligand-Target Pair
In DepthDetails PubMed