BDBM50599923 CHEMBL5204128
SMILES OC(=O)C1CC2(C1)CCN(CC2)c1ccc(NC(=O)c2nnc(Nc3ccc(F)c(F)c3)o2)cn1
InChI Key InChIKey=VUOQXGJJZVFPTI-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50599923
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetAcetyl-CoA acetyltransferase, mitochondrial(Homo sapiens)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis incubated for 1 hrs followed by 13C-addition of 13C-oleic a...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair