BDBM50600755 CHEMBL5171148

SMILES Nc1nc(cn2c1nc1ccccc21)C(=O)NCCc1ccccn1

InChI Key InChIKey=MWISIRXEPKXITJ-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50600755   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600755(CHEMBL5171148)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600755(CHEMBL5171148)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600755(CHEMBL5171148)
Affinity DataIC50:  647nMAssay Description:Antagonist activity at A2AAR in human HEK293 cells assessed as inhibition of CGS21680-induced cAMP production preincubated for 15 mins followed by CG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50600755(CHEMBL5171148)
Affinity DataEC50:  1.20nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed