BDBM50600758 CHEMBL5174275
SMILES Nc1nc(cn2c1nc1ccccc21)C(=O)NCc1ccncc1
InChI Key InChIKey=DBHBCVCCWMOUKI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50600758
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]ZM241385 from human A2AAR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by ...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by [3H]...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Antagonist activity at A2AAR in human HEK293 cells assessed as inhibition of CGS21680-induced cAMP production preincubated for 15 mins followed by CG...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair