BDBM50601490 CHEMBL5206263

SMILES COC(=O)[C@@H]1C[C@H](Nc2ncnc3n(nnc23)[C@H]2C[C@H](O)[C@H](COS(N)(=O)=O)C2)C=C1

InChI Key InChIKey=VARKRXJNUKYOEA-YYHQMBLXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50601490   

TargetNEDD8-activating enzyme E1 catalytic subunit(Homo sapiens)
Shanghai Institute Of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50601490(CHEMBL5206263)
Affinity DataIC50:  81nMAssay Description:Inhibition of NAE (unknown origin) mediated neddylation assessed as decrease in NEDD8-Ubcl2 adduct formation incubated for 2 hrs in presence of L-glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed