BDBM50601760 CHEMBL5180159::US11773078, Example 306
SMILES OCCN1CCN(CC1)c1ncc(Oc2cc(CN3CCC(CC(O)=O)CC3)cc(n2)-c2cc(Cl)cc(Cl)c2)cn1
InChI Key InChIKey=XZKGLRKBFXECOM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50601760
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Tev-FLAG-His-tagged furin (108 to 574 residues) (unknown origin) using FAM-QRVRRAVGIDK-TAMRA as substrate and measured after 2 hrsMore data for this Ligand-Target Pair
TargetFurin [108-574](Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development
US Patent
Glaxosmithkline Intellectual Property Development
US Patent
Affinity DataIC50: 1.26nMAssay Description:Reactions were performed in black 384-well polystyrene low volume plates (Greiner). Furin (108-574-Tev-Flag-His) enzyme was expressed and purified fr...More data for this Ligand-Target Pair