BDBM50602405 CHEMBL5205373

SMILES CCCC1CN(CC(=O)N2CCc3ccccc23)Cc2c1[nH]c(=O)c(C#N)c2-c1ccc(C)cc1

InChI Key InChIKey=TVUOEVCKUGISBU-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50602405   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Bayer

Curated by ChEMBL

LigandBDBM50602405(CHEMBL5205373)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Inhibition of full length human PDE9A expressed in Sf9 insect cells using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation cou...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI