BDBM50602900 CHEMBL5185704::US11814388, Compound 3

SMILES COc1ccc(Nc2ncnc3[nH]ccc23)cc1

InChI Key InChIKey=DJHHJFCJDPLIQB-UHFFFAOYSA-N

Data  2 IC50  4 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50602900   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602900(CHEMBL5185704 | US11814388, Compound 3)
Affinity DataKd:  3.00E+3nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602900(CHEMBL5185704 | US11814388, Compound 3)
Affinity DataKd:  2.80E+3nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetTau-tubulin kinase 2(Homo sapiens (Human))
Csic

Curated by ChEMBL
LigandPNGBDBM50602900(CHEMBL5185704 | US11814388, Compound 3)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602900(CHEMBL5185704 | US11814388, Compound 3)
Affinity DataKd:  1.20E+4nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetTau-tubulin kinase 1(Homo sapiens (Human))
Csic

Curated by ChEMBL
LigandPNGBDBM50602900(CHEMBL5185704 | US11814388, Compound 3)
Affinity DataIC50:  520nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAurora kinase A(Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602900(CHEMBL5185704 | US11814388, Compound 3)
Affinity DataKd:  3.50E+3nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent