BDBM50603092 CHEMBL5190509
SMILES CCNC(=O)c1ccc2N([C@@H](C)C[C@@H](Nc3ccc(cn3)C#N)c2c1)C(C)=O
InChI Key InChIKey=FQIILLCMQDMGGP-SCLBCKFNSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50603092
Affinity DataIC50: 200nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 30 mins in presence of fluorescent ligand by TR-FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins in presence of fluorescent ligand by TR-FRET methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
Affinity DataIC50: <3.98E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair