BDBM50603488 CHEMBL5205489

SMILES Nc1nn(-c2c3CCCCc3nc3ccc(cc23)[N+]([O-])=O)c2ncccc12

InChI Key InChIKey=QELNVWZDMSBUAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50603488   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50603488(CHEMBL5205489)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of amyloid beta (1 to 42 ) (unknown origin) self aggregation measured after 3 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50603488(CHEMBL5205489)
Affinity DataIC50:  56nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant AChE (32 to 614 residues) expressed in HEK293 cells using acetylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50603488(CHEMBL5205489)
Affinity DataIC50:  5.22E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant BuChE (29 to 602 residues) using butyrylthiocholine iodide as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed